Optimizing the SPECT Imaging Workflow For Individualized Dosimetry in Lu177-DOTATATE Treatment Of Progressive Metastatic Neoendocrine Tumors
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چکیده
منابع مشابه
Accuracy and precision assessment for activity quantification in individualized dosimetry of 177Lu-DOTATATE therapy
BACKGROUND In order to obtain a reliable 177Lu-DOTATATE therapy dosimetry, it is crucial to acquire accurate and precise activity measurements with the radionuclide calibrator, the SPECT/CT camera, and the NaI(Tl) well counter. The aim of this study was to determine, in a clinical context, the accuracy and the precision of their activity quantification over a range of activities and time. Ninet...
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The Utility of Diffusion Weighted Magnetic Resonance Imaging in Detection of the Origin of the Brain Solid Metastatic Tumors
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Objective(s): 68Ga-DOTATATE positron emission tomography (PET)/computed tomography (CT) has shown promising results in imaging of neural crest tumors (NCT). Herein, we compared the performance of 68Ga-DOTATATE PET/CT and 131I-MIBG single photon emission computed tomography (SPECT)/CT in the initial diagnosis, staging and follow-up of pa...
متن کاملImproving quantitative dosimetry in 177Lu-DOTATATE SPECT by energy window-based scatter corrections
PURPOSE Patient-specific dosimetry of lutetium-177 ((177)Lu)-DOTATATE treatment in neuroendocrine tumours is important, because uptake differs across patients. Single photon emission computer tomography (SPECT)-based dosimetry requires a conversion factor between the obtained counts and the activity, which depends on the collimator type, the utilized energy windows and the applied scatter corre...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2020
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2020.07.1803